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Murakami’s 11th HR, Domínguez’s 6th save lead White Sox to 5-4 win over the Nationals

Munetaka Murakami hit his 11th homer of the season and reliever Seranthony Domínguez struck out two in the ninth inning as the White Sox beat the Washington Nationals 5-4 on Friday night.

The White Sox have won four of their last five games. Munetaka has hit a home run in six of the last seven games and moved into a tie with Houston's Yordan Alvarez for the MLB lead.

Munetaka's latest homer was a 415-foot shot to center field in the fourth inning.

Domínguez entered in the ninth and struck out Nasim Nuñez, and coaxed José Tena into a ground out. With the potential tying run at third base, Nationals leadoff hitter James Wood — who has the fourth-best OPS in the league — struck out swinging and Domínguez earned his sixth save.

Jordan Leasure (2-0) struck out one in one inning and gave up a home run to Brady House.

The Nationals scored first on a sacrifice fly by Luis García Jr. in the second, and scored two more runs in the fifth. Reliever Riley Cornelio (0-1) pitched two innings, walking four batters. He allowed earned runs and had a strikeout in his MLB debut.

Colson Montgomery and Tristan Peters hit RBI singles and Luisangel Acuña scored in the seventh as the White Sox took their first lead in the game.

Up next

The Nationals send Jake Irvin (1-3, 6.00 ERA) against Chicago's Noah Schultz (1-1, 3.86 ERA) on Saturday.

Chicago White Sox's Munetaka Murakami celebrates after hitting a solo home run during the fourth inning of a baseball game against the Washington Nationals in Chicago, Friday, April 24, 2026. (AP Photo/Paul Beaty) (AP Photo/Paul Beaty)
Chicago White Sox's Luisangel Acuna (0) scores on an Andrew Benintendi sacrifice fly while Washington Nationals catcher Drew Millas, right, attempts to apply a tag during the seventh inning of a baseball game in Chicago, Friday, April 24, 2026. (AP Photo/Paul Beaty) (AP Photo/Paul Beaty)
Chicago White Sox's Colin Montomery watches his RBI single during the sixth inning of a baseball game against the Washington Nationals in Chicago, Friday, April 24, 2026. (AP Photo/Paul Beaty) (AP Photo/Paul Beaty)