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The Latest: Germany's health minister tours vaccine center

BERLIN -- Germany's health minister toured a new vaccination center in Duesseldorf on Tuesday, preparing for possible mass vaccinations against the coronavirus in the coming weeks.

Vaccinations in Germany will be free, voluntary and people will receive letters about when it's their turn for the shot, Health Minister Jens Spahn says.

The first shots will be given either in vaccination centers around the country or by mobile medical teams who will go to nursing homes to vaccinate the most vulnerable people. Later next year, doctors will vaccinate people at their local practices, the health minister says.

Spahn expects Germany to receive five to eight million doses of vaccine developed by Pfizer and BioNTech as well as by Moderna.

There will be 53 centers opened in Germany's most populous state of North Rhine-Westphalia, with 18 million people, where Duesseldorf is based. In Berlin, home to 3.6 million people, six centers are being prepared.

In Germany, there were 13,604 confirmed cases and 388 deaths in the last 24 hours.

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THE VIRUS OUTBREAK:

- BioNTech and Pfizer ask European regulator for expedited approval of coronavirus vaccine

- Americans face new COVID-19 restrictions after Thanksgiving

- At tiny rural hospitals, exhausted medical workers t reat friends and family

- Formula 1 champion Lewis Hamilton tests positive for coronavirus

- U.K. stocks up on vaccines, hopes to start virus shots within days

- Virus forces businesses to adapt or close down on the streets of London

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Follow AP's coverage at https://apnews.com/hub/coronavirus-pandemic and https://apnews.com/UnderstandingtheOutbreak

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HERE'S WHAT ELSE IS HAPPENING:

PROVIDENCE, R.I. - Rhode Island has opened two field hospitals with a combined 900 beds to deal with an expected increase of COVID-19 patients.

Care New England opened a field hospital with more than 300 beds in Cranston on Monday, the same day the state sent an emergency alert saying conventional hospitals had reached their coronavirus capacity.

A facility with nearly 600 beds opened Tuesday at the Rhode Island Convention Center in Providence. It is run by Lifespan, the state's largest hospital group.

There were 365 COVID-19 patients in the state's hospitals on Saturday, according to the state Department of Health. That's down from a high of 381 on Nov. 23.

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ISLAMABAD - A top Pakistani health official says Islamabad plans to procure a COVID-19 vaccine in the first quarter of next year.

The announcement Tuesday by Faisal Sultan came hours after Pakistan registered 67 more deaths and 2,458 new coronavirus cases.

Pakistan has allocated $150 million to acquire vaccine, which first will be administered to frontline health workers and elderly people.

The government has imposed a partial lockdown in many areas across Pakistan. Authorities have asked people to adhere to social distancing rules to avoid stricter measures.

Pakistan's death toll stands at 8,091 and more than 400,000 confirmed cases.

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MADRID - Madrid officials held a ceremony to open part of a 1,000-bed hospital for emergencies. About 200 health professionals gathered Tuesday at the Nurse Isabel Zendal Hospital, built in 100 days at a cost of 100 million euros ($119 million), twice the original budget.

Health workers' unions say the investment should had instead gone to shore up an existing public health system run down by years of spending cuts.

The regional Madrid president, Isabel Díaz Ayuso, says it will help alleviate pressure in other public hospitals by focusing on COVID-19 patients. Its located near Madrid's international airport.

The conservative regional leader has been a critic of the pandemic's handling by the leftist national government led by Prime Minister Pedro Sánchez, constantly objecting to preventative measures and advocating for restrictions to preserve economic activity. Some critics say the new hospital is no more than a vanity project for Díaz Ayuso, a building with beds not ready to receive patients.

The region's 14-day infection rate has dropped from 500-plus cases per 100,000 inhabitants in October to 236 on Monday, below the national average of 275.

Spain has reported 1.6 million coronavirus cases and more than 45,000 confirmed deaths.

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SAKHIR, Bahrain - Seven-time Formula One champion Lewis Hamilton has tested positive for the coronavirus and will miss this weekend's Sakhir Grand Prix.

The Mercedes team says Hamilton tested negative three times last week but woke feeling mild symptoms the morning after winning Sunday's Bahrain Grand Prix.

Hamilton took another test after being informed that a contact prior to arrival in Bahrain had subsequently tested positive. The 35-year-old British driver returned the positive test Monday and the result has been confirmed by a retest.

Hamilton is in isolation in accordance with the health protocols in Bahrain and has mild symptoms, the team says.

Hamilton has won 11 races this season and clinched the drivers' championship last month in Turkey. He's the third F1 driver to test positive this season.

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THE HAGUE, Netherlands - A three-month Dutch law to rein in the spread of the coronavirus began on Tuesday.

The law requires wearing face masks in public indoor areas, including stores, museums, libraries and theaters. Masks are now mandatory in all schools except primary schools, although they can be taken off once students are in classrooms.

Before the law, masks were only required when traveling on public transport.

The seven-day rolling average of daily new cases in Netherlands has eased slightly over the past two weeks from 32 new cases per 100,000 people on Nov. 16 to 28 on Monday.

Also Tuesday, the Dutch health minister Hugo de Jonge says the Netherlands could begin coronavirus vaccinations by Jan. 4.

The minister says if the vaccine candidate by Pfizer and BioNTech is approved later this month, he expects delivery of about 1 million doses of its vaccine to the Netherlands in December and 1.6 million doses in the first quarter of 2021.

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GAZA CITY, Gaza Strip - The Islamic militant group Hamas says its leader in the Gaza Strip has contracted the coronavirus.

Hamas says Yehiya Sinwar was tested after he showed symptoms and the infection was confirmed. It says he is 'œin good health and conducting his work with adherence to safety measures.'ť

Hamas has ruled Gaza since taking over the territory from the rival Palestinian Authority in 2007. Sinwar has led the group in Gaza, its central base, since 2017.

Previously, he spent two decades in Israeli prisons after being convicted of planning an operation in which two Israelis were killed. He was freed in a 2011 prisoner swap between Israel and Hamas.

Gaza, which is under a tight Israeli-Egyptian blockade, reported its first case of community transmission of coronavirus in August. Since then, the outbreak has quickly spread.

Health authorities have confirmed 21,000 cases and 111 deaths, including a record nine deaths reported on Tuesday.

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TOKYO - Tokyo Gov. Yuriko Koike is asking senior citizens 65 or older and those with underlying health conditions not to use the government's GoTo discount campaign to travel in and out of Tokyo.

New cases in Tokyo and other major cities have spiked in recent weeks, with serious cases rapidly filling hospitals and impacting the treatment of other patients.

Koike says she is focusing on how to stop serious cases and prevent the medical systems from collapsing.

Koike issued a request for restaurants serving alcohol, bars and karaoke chains to close early until mid-December. Aichi, Osaka and Hokkaido have taken similar steps.

Prime Minister Yoshihide Suga's government has been criticized for being slow to curb social and economic activity. Suga hasn't taken tougher steps beyond basic safety precautions and wearing masks.

Japan managed to avoid a high number of cases with stay at home and business closure requests under a non-binding state of emergency in the spring. Some experts say it's time to scale back business activity and urged the government to act quickly to avoid another state of emergency.

The health ministry says Japan has nearly 149,000 confirmed coronavirus cases and more than 2,100 deaths.

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BERLIN - Germany's science minister says the same safety standards are applied in the approval process for coronavirus vaccines as for other drugs.

Anja Karliczek says ensuring the same standards is key to gaining the widest possible public acceptance for the COVID-19 vaccine.

Karliczek noted that the European Medicines Agency will be holding a public hearing on Dec. 11 on an approval request by German pharmaceutical company BioNTech and its U.S. partner Pfizer.

She says the vaccine will be voluntary and authorities will work hard to inform the public about possible side effects that might be excepted after immunization, such as headaches, localized pain and fever.

Marylyn Addo, a doctor at Hamburg's UKE hospital who is involved in the trials for a rival vaccine, says the rapid development of a vaccine was the result of enormous efforts by scientists, early funding and experience from previous vaccines.

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BERLIN - German pharmaceutical company BioNTech and its U.S. partner Pfizer say they have submitted an application for expedited approval of their coronavirus vaccine with the European Medicines Agency.

The two companies say the submission, which occurred Monday, completes the rolling review process they initiated with the agency on Oct. 6.

The move comes a day after rival Moderna said it was asking U.S. and European regulators to allow emergency use of its COVID-19 vaccine.

BioNTech says if the vaccine, currently named BNT162b2, is approved, its use in Europe could begin before the end of 2020.

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ROUEN, France - Lockdowns that are forcing millions of people to once again stay home - cutting them off from families and friends, shuttering businesses they invested in, university classes that fed their minds and the nightspots where they socialized - has begun to turn back the coronavirus resurgence in France.

Still, in the country that passed the bleak milestone of 52,000 dead in November, the costs to mental health have been considerable.

With numbers now falling for COVID-19 patients in intensive care, psychiatrists are facing a follow-up wave of psychological distress. Health authorities' surveys point to a surge of depression most acute among people without work, those in financial hardship and young adults.

The Rouvray Hospital Center in the Normandy town of Rouen is among places where psychiatrists are on the front line of the pandemic's mental-health fallout. They are fearful that a growing crisis of depression, anxiety and worse may be on the horizon as more livelihoods, futures and hopes are lost to the pandemic.

Associated Press journalists spent 10 hours in the sprawling 535-bed facility, the day after French President Emmanuel Macron laid out a blueprint stretching into mid-January for the gradual lifting of lockdown restrictions.

'œBeing alone between four walls is terrible,'ť one patient says. 'œThe halting of life like this, it reverberates on people. It is not good.'ť

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BRUSSELS - Nonessential shops in Belgium were reopening Tuesday in the wake of encouraging figures about declining daily coronavirus infection rates and hospital admissions.

However, the government is concerned the change might lead to massive gatherings in the nation's most popular shopping centers and streets. Over the weekend, pre-Christmas light festivals already led to crowded scenes in several cities, prompting warnings from virologists about the dangers of reopening too soon.

Belgium, host to the headquarters of the 27-nation European Union, has been one of the hardest-hit countries in Europe during the pandemic. Belgium has reported more than 16,500 deaths linked to the virus during two surges in the spring and the fall.

Under the new rules, shopping time is limited to half an hour. Restaurants and bars remain closed.

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UNITED NATIONS - Nobel Peace Prize laureate Nadia Murad says the COVID-19 pandemic has increased trafficking of women and gender-based violence, leaving the health and safety of women 'œon the line.'ť

The 27-year-old activist, who was forced into sexual slavery by Islamic State fighters in Iraq, says curfews, lockdowns and travel restrictions imposed by governments to slow the spread of the virus 'œhave had unintended consequences on women worldwide.'ť

Murad said domestic tensions have intensified in confined living spaces, and stay-at-home orders 'œare increasing human trafficking farther underground, out of sight of law enforcement.'ť

A member of Iraq's Yazidi minority, Murad was among thousands of women and girls who were captured and forced into sexual slavery by Islamic State extremists in 2014. Her mother and six brothers were killed by Islamic State fighters. She became an activist on behalf of women and girls after escaping and finding refuge in Germany, and shared the Nobel Peace Prize in 2018.

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HANOI, Vietnam - Vietnamese authorities are conducting intensive contact tracing after the country's first confirmed local transmission of the coronavirus in 89 days.

State media says a 32-year-old man in Ho Chi Minh City tested positive for the coronavirus on Monday after visiting a flight attendant who was undergoing self-quarantine following his return from Japan two weeks ago. The flight attendant tested positive on Saturday, the Tuoi Tre newspaper said.

Health authorities ordered 137 people who had been in close contact with the man to stay in a central quarantine facility and shut down an English center where the man works as a teacher.

Vietnam's borders remain closed in an attempt to keep out the virus. Only limited international flights are operating to repatriate Vietnamese nationals and transport foreign diplomats and experts.

The country has reported 1,347 coronavirus cases, including 35 deaths.

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HONG KONG - Hong Kong leader Carrie Lam on Tuesday urged residents to stay home as the city grapples with a resurgence of the coronavirus, which has infected over 500 people in the past week.

Lam asked citizens to 'œrefrain from social gatherings'ť and people, in particular the elderly, should remain at home.

'œThe latest wave of the epidemic is rather severe. Every one of us should do our best and exercise a high level of discipline to fight the pandemic,'ť she said at a news conference. 'œThe coming two weeks is a crucial period.'ť

Many of the new infections in Hong Kong have been tied to dance studios, and outbreaks have also been found among staff and guests at several restaurants.

The new wave of infections has led authorities to tighten social distancing restrictions, including closing entertainment venues such as karaoke bars and game centers and limiting public gatherings to two people.

The growing number of cases has delayed a 'œtravel bubble'ť between Singapore and Hong Kong initially slated for November.

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MANILA, Philippines - Coronavirus quarantine restrictions will remain imposed in the Philippine capital during the Christmas season this month and officials say they will ban big Christmas parties.

President Rodrigo Duterte said in televised remarks late Monday that aside from Metropolitan Manila, the bustling capital region of more than 12 million, the 'œgeneral community quarantine'ť would be imposed in seven other cities and provinces in December.

The restrictions ban large public gatherings, in-school classes and entertainment businesses. It allows shopping malls, restaurants and essential shops, including barber shops, to operate with required safeguards. Those include wearing masks and shields and social distancing.

Duterte lamented the "hard-headedness" of some citizens who defy quarantine restrictions or wearing of masks.

The Philippines has more than 431,600 confirmed coronavirus infections, the second-highest in Southeast Asia. There's been 8,392 reported deaths.

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UNITED NATIONS - The head of the world's largest humanitarian network is urging governments and institutions to combat 'œfake news'ť about COVID-19 vaccines and start building trust about the importance of vaccinating people.

Francesco Rocca, president of the International Federation of Red Cross and Red Crescent Societies, says 'œto beat this pandemic, we also have to defeat the parallel pandemic of distrust.'ť

He says there is 'œa growing hesitancy about vaccines in general, and about a COVID vaccine in particular'ť around the world, pointing to a recent Johns Hopkins University study in 67 countries that found vaccine acceptance declined significantly in most countries from July to October this year.

In a quarter of countries, Rocca said, the study found that the acceptance rate for a vaccine against the coronavirus was near or below 50 percent, with Japan dropping from 70 percent to 50 percent acceptance, and France dropping from 51 percent to 38 percent acceptance.

He stressed the lack of trust 'œis by no means a Western phenomenon,'ť citing the federation's research in recent months in eight African countries showed a steady decline in the perceptions of the risk of COVID-19 infection.

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One of around 200 health professionals protest at the entrance of the Nurse Isabel Zendal Hospital as officials entered the state-of-the-art facility, built in 100 days at a cost of 100 million euros (119 dolllars), twice the original budget in Madrid, Spain, Tuesday, Dec. 1, 2020. Authorities in Madrid held a ceremony to open part of a 1,000-bed hospital for emergencies that critics say is no more than a vanity project, a building with beds not ready to receive patients and unnecessary now that contagion and hospitalizations are waning. Spain has officially logged 1.6 million infections and over 45,000 deaths confirmed for COVID-19 since the beginning of the year. Message on mask reads ' Public heath service'. (AP Photo/Paul White) The Associated Press
Tokyo Gov. Yuriko Koike speaks during a news conference Wednesday, Nov. 25, 2020, in Tokyo. The board reads "infection control measures, Short and intensive." (Kyodo News via AP) The Associated Press
FILE - In this Saturday, Nov. 28, 2020 file photo Mercedes driver Lewis Hamilton of Britain gestures after taking the pole position after the qualifying session at the Formula One Bahrain International Circuit in Sakhir, Bahrain. World champion Lewis Hamilton tested positive for COVID-19 and will miss the Sakhir Grand Prix this weekend, his Mercedes-AMG Petronas F1 Team said Tuesday Dec. 1, 2020. (Hamad Mohammed, Pool via AP, File) The Associated Press
A medical workers works in a COVID-19 set up for rapid new coronavirus testing in Vienna, Austria, Monday, Nov. 30, 2020. The Austrian government has moved to restrict freedom of movement for people, in an effort to slow the onset of the COVID-19 disease and the spread of the coronavirus. (AP Photo/Ronald Zak) The Associated Press
Medical personnel transfer a COVID-19 patient from a state to a private clinic which has been appropriated, in the northern city of Thessaloniki, Greece, Sunday, Nov. 29, 2020. Greece's Health ministry has forcibly appropriated two clinics and their staff in the country's second populated city, where the outbreak is the most severe. (AP Photo/Achilleas Chiras) The Associated Press
People wearing masks to help protect against the spread of coronavirus, walk along a popular street in Ankara, Turkey, Friday, Nov. 27, 2020. Turkey's COVID-19 fatalities continue to rise, hitting another record Sunday, Nov 29, 2020, with 185 new deaths. The Turkish government resumed reporting all positive cases this week after only reporting symptomatic patients for four months. Night-time curfews over the weekend are in effect for a second week across the country but media reports show packed public spaces during the day. (AP Photo/Burhan Ozbilici) The Associated Press
A man shows a negative COVID-19 test together with his cellphone QR code in a set up for rapid new coronavirus testing in Vienna, Austria, Monday, Nov. 30, 2020. The Austrian government has moved to restrict freedom of movement for people, in an effort to slow the onset of the COVID-19 disease and the spread of the coronavirus. (AP Photo/Ronald Zak) The Associated Press
In this handout photo provided by the Malacanang Presidential Photographers Division, Philippine President Rodrigo Duterte speaks as he meets members of the Inter-Agency Task Force on the Emerging Infectious Diseases at the Malacanang presidential palace in Manila, Philippines on Monday Nov. 30, 2020. Coronavirus quarantine restrictions will remain imposed in the Philippine capital during the Christmas season this month and officials said they will ban big Christmas parties in Asia's largest Roman Catholic nation to prevent new infection spikes. (Karl Norman Alonzo/Malacanang Presidential Photographers Division via AP) The Associated Press
A person wearing a mask runs on a path in front of the Golden Gate Bridge during the coronavirus pandemic in San Francisco, Monday, Nov. 30, 2020. (AP Photo/Jeff Chiu) The Associated Press
Pedestrians and trams on the street decorated with Christmas lights in downtown Zagreb, Croatia, Monday, Nov. 30, 2020. Most of Advent activities in the city have been cancelled due to Covid-19 pandemic. (AP Photo/Darko Bandic) The Associated Press
Around 200 health professionals protest at the entrance of the Nurse Isabel Zendal Hospital as officials entered the state-of-the-art facility, built in 100 days at a cost of 100 million euros (119 dolllars), twice the original budget in Madrid, Spain, Tuesday, Dec. 1, 2020. Authorities in Madrid held a ceremony to open part of a 1,000-bed hospital for emergencies that critics say is no more than a vanity project, a building with beds not ready to receive patients and unnecessary now that contagion and hospitalizations are waning. Spain has officially logged 1.6 million infections and over 45,000 deaths confirmed for COVID-19 since the beginning of the year. (AP Photo/Paul White) The Associated Press
New wheelchairs sit in the empty Isabel Zendal new hospital during the official opening in Madrid, Spain, Tuesday, Dec. 1, 2020. Authorities in Madrid are holding a ceremony to open part of a 1,000-bed hospital for emergencies that critics say is no more than a vanity project, a building with beds not ready to receive patients and unnecessary now that contagion and hospitalizations are waning. Spain has officially logged 1.6 million infections and over 45,000 deaths confirmed for COVID-19 since the beginning of the year. (AP Photo/Paul White) The Associated Press
A desk with computer screens and new beds sit in the empty Isabel Zendal new hospital during the official opening in Madrid, Spain, Tuesday, Dec. 1, 2020. Authorities in Madrid are holding a ceremony to open part of a 1,000-bed hospital for emergencies that critics say is no more than a vanity project, a building with beds not ready to receive patients and unnecessary now that contagion and hospitalizations are waning. Spain has officially logged 1.6 million infections and over 45,000 deaths confirmed for COVID-19 since the beginning of the year. (AP Photo/Paul White) The Associated Press
People wearing face masks to protect against the spread of the coronavirus walk through China Town in Yokohama, Kanagawa prefecture, near Tokyo, Tuesday, Dec. 1, 2020. (AP Photo/Koji Sasahara) The Associated Press
A man entering the national library in The Hague, Netherlands, Tuesday, Dec. 1, 2020, passes a sign informing visitors to wear mandatory face masks. Wearing face masks in publicly accessible indoor venues such as libraries, museums became obligatory in the Netherlands on Dec. 1, 2020, when a new temporary law underpinning existing government coronavirus restrictions came into force. (AP Photo/Peter Dejong) The Associated Press
People wearing face masks to protect against the spread of the coronavirus walk under the yellow leaves of ginko trees in Yokohama, Kanagawa prefecture, near Tokyo, Tuesday, Dec. 1, 2020. (AP Photo/Koji Sasahara) The Associated Press
People wearing face masks to prevent the spread of the coronavirus wait in a line to enter a shop in Liege, Belgium, Tuesday, Dec. 1, 2020. Non-essential shops in Belgium are reopening on Tuesday in the wake of encouraging figures about declining infection rates and hospital admissions because of the coronavirus. (AP Photo/Valentin Bianchi) The Associated Press
Tim Smith, of Boston, receives a free COVID-19 test given by Health Innovations, Tuesday, Dec. 1, 2020, in Chelsea, Mass. (AP Photo/Elise Amendola) The Associated Press
People wait in line to be tested for COVID-19, Tuesday, Dec. 1, 2020, in Miami Beach, Fla. (AP Photo/Marta Lavandier The Associated Press
A person walks past an information sign for a vaccination center at a soccer stadium, home of German second division team Fortuna Duesseldorf, in Duesseldorf, Germany, Tuesday, Dec. 1, 2020. The German government is preparing to roll out a nationwide coronavirus vaccination program. (Federico Gambarini/dpa via AP) The Associated Press
The vaccination booth 'B' is pictured in a vaccination center in a soccer stadium, home of German second division team Fortuna Duesseldorf, in Duesseldorf, Germany, Tuesday, Dec. 1, 2020. The German government is preparing to roll out a nationwide coronavirus vaccination program. (Federico Gambarini/dpa via AP) The Associated Press
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