Sheets the winner in Santana's debut at Shea

Ben Sheets ruined Johan Santana's Shea Stadium debut, outpitching the Mets' new ace in the Milwaukee Brewers' 5-3 win over host New York on Saturday.

Home runs by Bill Hall, Rickie Weeks and Gabe Kapler helped Milwaukee come from behind and Sheets (2-0) overcame a shaky start to help Brewers end a three-game losing streak.

Santana (1-2) struggled, and the Mets' three-game winning streak was snapped. He lasted 6¿ innings and allowed 5 runs and 6 hits with 2 walks, striking out seven and throwing two wild pitches.

Sheets allowed 3 runs and 5 hits in 7¿ innings with 5 strikeouts and 2 walks. After giving up two runs in the first inning and leaving the bases loaded in the second, he was untouchable, retiring 18 consecutive batters into the eighth inning.

Braves 10, Nationals 2: Jeff Francoeur had 2 home runs and a career-high 7 RBI, and Atlanta handed Washington its ninth straight loss. Francoeur hit a 3-run home run in the first inning, a 2-run single in the fourth and a 2-run shot in the sixth.

Diamondbacks 10, Rockies 3: Justin Upton went 3-for-3 with 4 RBI, including a 3-run home run, to power host Arizona past Colorado for its eighth consecutive victory. The 20-year-old outfielder boosted his average to .415, including 5 home runs with 10 RBI.

Cardinals 8, Giants 7 (10): Chris Duncan lined a go-ahead single to left with the bases loaded in the 10th inning, and visiting St. Louis battered the San Francisco bullpen to spoil a gem by Giants starter Matt Cain, who had a no-hitter heading into the seventh. Albert Pujols ended it with a leadoff double.

Pirates 4, Reds 3: Nate McLouth, the surprise major-league hits leader, singled in the go-ahead run and had 2 more hits, and host Pittsburgh won consecutive games for the first time this season, beating Cincinnati.

Astros 5, Marlins 0: Brandon Backe (1-1) gave up 5 hits and 5 walks with 2 strikeouts in 5 innings, and Lance Berkman hit a 2-run homer as host Houston beat Florida.

American League

Red Sox 4, Yankees 3: Manny Ramirez homered and added a 2-run double to give Boston the lead, and Josh Beckett (1-1) rebounded from a bad season debut to lead the host Red Sox over New York. Beckett allowed 1 questionable hit in the first 5 innings, and 5 hits in all.

Twins 2, Royals 0: Boof Bonser (1-2) pitched 6 innings, and Jason Kubel homered and scored twice as Minnesota shut out Kansas City for the second straight night.

Orioles 3, Rays 2: Ramon Hernandez hit a tiebreaking solo homer in the ninth inning, after a run-scoring triple, and Baltimore stopped a three-game skid by beating host Tampa Bay.

Athletics 7, Indians 3: Bobby Crosby hit a 3-run homer and Oakland took advantage of 10 walks issued by Cleveland pitchers. Fausto Carmona (1-1), two days after signing a seven-year, $48 million contract extension, gave up a career-high 8 walks in 3½ innings.