MILWAUKEE -- Chase Headley homered in the top of the 12th inning and San Diego relievers tossed six shutout innings in the Padres' 2-1 win Tuesday night over the Milwaukee Brewers.
Huston Street retired the side in order in the bottom of the 12th for his seventh save after Donn Roach (1-0) allowed just one hit over two scoreless innings.
Headley's homer to center off a 1-0 fastball from Alfredo Figaro (0-1) was one of the few mistakes from the mound among teams with two of the best staff ERAs in baseball. Padres starter Ian Kennedy labored through six innings while Brewers counterpart Yovani Gallardo went seven strong innings before the bullpens took over.
The Padres' bullpen allowed three hits and struck out eight to snap Milwaukee's four-game winning streak.
Street caught slugger Ryan Braun looking while leaning back on a slider for a strikeout to end the four-hour game.
Both teams squandered earlier scoring opportunities. With a runner on second, first baseman Mark Reynolds went to his knees to pick up a hard bouncer down the line from Everth Cabrera for the third out in the top of the 10th inning.
Milwaukee's Khris Davis left runners on first and second to end the bottom of the 10th after flying out against Roach. An inning earlier, reliever Dale Thayer left runner Jean Segura stranded on second after striking out pinch-hitter Rickie Weeks and getting Carlos Gomez to fly out softly to center.
This is the type of close game that the Brewers have been winning in building the best record in baseball at 15-5 entering Tuesday night's game.
Against the Padres, one mistake by Figaro cost them. The righty called up Monday to help out an already taxed relief corps allowed just two hits and struck out three in three innings.
Each starting pitcher had what appeared to be minor health scares. Scooter Gennett homered to right on a 3-1 fastball to tie the game at 1 in the fifth, a couple pitches after Kennedy called for the trainer after pointing to his right leg. Kennedy appeared to suffer a cramp, but stayed in the game after taking a few warm-up tosses.
It was an active inning for Kennedy, who squeezed home Yonder Alonso from third in the top of the inning after Gallardo couldn't cleanly field a bunt down the third-base line with the runner charging home. Gallardo would get out of the inning two batters later after fielding a liner off his right leg from Will Venable that the veteran righty turned into an out at first.
Gallardo walked slowly back to the dugout and kicked his glove before reaching the steps. It was the only blemish in an otherwise stellar outing for the bearded righty, who lowered his ERA to 1.42 but got his third straight no-decision.
Notes: The Padres acquired INF Tyler Greene on Tuesday from the Atlanta Braves for a player to be named. Greene was assigned to Triple-A El Paso. He was hitting .200 with one homer and four RBIs in 12 games at Triple-A Gwinnett in the Braves system. ... RHP Johnny Hellweg, one of the top prospects in the Brewers farm system, has been diagnosed with an ulnar collateral ligament injury after leaving Sunday's game for Triple-A Nashville. He is scheduled to see Dr. James Andrews for a second opinion next week. ... Tyson Ross (2-2), who turned 27 on Tuesday, will get the start Wednesday when the Padres wrap up their three-game set in Milwaukee. Kyle Lohse (3-1) starts for the Brewers.