Russell Mitchell tied the game with a two-out homer in the ninth inning, and Juan Castro had the go-ahead single in a three-run 10th as the Los Angeles Dodgers rallied to beat the Chicago White Sox 6-4 on Friday night.
Jamey Carroll started the 10th with a single off Sergio Santos (2-1) for his fourth hit, and Matt Kemp singled one out later.
Castro, a seventh-inning replacement after second baseman Juan Uribe left with a hip flexor injury, then dumped an RBI single over first base. James Loney followed with an RBI double, and Jay Gibbons greeted Will Ohman with a run-scoring single.
No. 9 hitter Mitchell, who entered batting .091 and was 0 for 3, tied it with a drive down the left field line off Santos, who had not given up a run all season over 20 innings. He blew his first save in seven chances. It was Mitchell's first homer of the year.
Kenley Jansen (1-0) pitched two scoreless innings for the win. The White Sox had runners on second and third with one out against Matt Guerrier in the 10th. Adam Dunn hit an RBI grounder off Scott Elbert before Mike MacDougal got Paul Konerko on a grounder for his first save in his first chance.
Trailing 3-2, the Dodgers loaded the bases against Matt Thornton in the eighth before Jesse Crain struck out Castro and retired Loney on a grounder.
Chicago starter Phil Humber pitched seven solid innings, allowing a two-run homer to Kemp in the first, and left with a 3-2 lead.
Gordon Beckham, in a 2-for-22 slump, hit a two-run homer as Chicago scored three in the second off Ted Lilly. Lilly, who took a no-hitter into the ninth inning against the White Sox last June while pitching for the Cubs at Wrigley Field, allowed seven hits and three runs in seven innings.
The teams met in the 1959 World Series -- won by the Dodgers in six games-- and they're hardly strangers these days because they share a spring training complex in Glendale, Ariz. The announced attendance on a second straight foggy night at U.S. Cellular Field was 24,121.
Beckham's fourth homer came right after back-to-back, two-out doubles by Alex Rios and Ramon Castro. The White Sox had five consecutive hits, and six straight batters reached before Lilly fanned Alexei Ramirez to end the inning.
Dodgers outfielder Andre Ethier, who earlier this season had a 30-game hitting streak, singled in the third to snap an 0-for-22 slump. He was 1-for-4.
Notes: Dodgers right-hander Jon Garland will pitch at U.S. Cellular Field on Saturday for the first time since 2007, his final season with the White Sox. He'll be opposing his friend and former teammate Mark Buehrle. The two still text occasionally. Garland was 92-81 in eight seasons with Chicago and an 18-game winner in 2005 and 2006. He pitched a complete game against the Angels in the 2005 ALCS to help the White Sox make the World Series where they swept Houston. In the Game 4 clincher, Uribe made two stellar defensive plays from shortstop, falling into the stands to catch a pop and then fielding a slow grounder and making a quick throw to get the final out. Both Garland and Uribe were honored in a scoreboard tribute before Friday's game. They watched from the dugout and then tipped their caps to the crowd. Uribe, playing second, made a nice diving catch of Alex Rios' pop to end the third. ... The White Sox were 15-3 in interleague play last year.